Gastrin: A Gastrointestinal Hormone

Gastrointestinal hormones are biologically active polypeptides secreted from the endocrine cells of the GIT mucosa. These hormones enter the portal circulation, then flow into the systemic circulation, and finally reach the target tissue. Some gastrointestinal hormones also function as paracrine and autocrine hormones to regulate gastrointestinal (GI) functions. They are chemical messengers.