Purpura| Clotting| Bleeding Time 

    This article is to provide knowledge of Purpura, a very common condition the public suffers from. How it is produced, our line of treatment, and much more.

Introduction

Purpura is a clinical condition in which there is a tendency for spontaneous bleeding, usually beneath the skin, mucous membrane, and internal organs. In this condition, bleeding time is prolonged (average is 2 to 6 minutes.), but clotting time is average (standard is five to10 minutes).https://learn-and-fly.co.in/2021/12/26/what-is-bloodcompositionfunctions/(opens in a new tab)

Table of contents

1. Introduction
   1. Classification of purpura   
   2. Normal count of Platelets
   3. Average Bleeding time
      1. Average clotting time
   4. Sign and symptoms
   5. Diagnosis
2. Treatment 

Classification of purpura   

 Purpura may be classified as

1.	Primary or Idiopaheic or Congenital Autoimmune
2.	Secondary or symptomatic Allergic Infection Certain drugs Cachectic

   

   

   

Normal count of Platelets

The average count of platelets is 1.5 lac to 4 lac per cubic millimeter of blood.

Average Bleeding time

The average bleeding time is 2 to 6 minutes.

Average clotting time

The average clotting time is five to 10 minutes.

Sign and symptoms

Spontaneous bleeding, usually beneath the skin, mucous membrane, and internal organs.

Diagnosis

Bleeding time is estimated. It is more than the average value. How to determine the bleeding time https://blog.totalphysiology.com/2021/09/how-to-determine-bleeding-and-clotting.html

1. Thrombocytopenic purpura-platelet count is 50-10 thousand per cubic milliliter of blood.

2. Thromboasthenic purpura platelet count is average, but the function is abnormal.

Purpura hemorrhagic is severe purpura with bleeding in the skin, mucous membrane, and internal organs and is usually fatal.

Primary purpura is also known as idiopathic, congenital, or hereditary.

I.T.P = Idiopathic thrombocytopenic purpura is due to autoantibodies against platelet membrane glycoprotein IIb-IIa, which causes premature removal of platelets from the reticuloendothelial system.

Allergic purpura is due to some allergies.

Infection by yellow fever, typhus, or infective endocarditis may cause purpura.

Certain drugs, e.g., Iodide, bismuth, ergots, etc., may cause purpura.

Cachectic state: in some cancers, the purpura may occur.

Treatment 

1)      Small dose of corticoids.

2)      Splenectomy.

3)      I.V. infusion of immunoglobulins.

4)      Platelet transfusion.

Intravenous (I.V.) infusion is a slow therapeutic introduction of fluid other than blood into a vein.

Transfusion, also known as blood transfusion, is the transfer of blood or a blood component, such as plasma or platelets, from one person to another in the vein.

Disclaimer

This article is about academic-health-related topics and not for treatment purposes. If you have any problems, consult a qualified medical professional.