AKI is described as a clinical syndrome due to a sudden (within hours to a maximum of seven days)decrease in renal function to the point that waste products accumulate in the body. AKI causes structural damage and loss of function.
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Renal Clearance Formula and Its Importance
The renal clearance value of a given substance is the volume of plasma in milliliter wholly cleared of that given substance in one minute by the kidneys; it is expressed as ml per minute( ml/minute).
Clearance compares the amount of substance removed from the plasma per unit time for permanent with the amount of substance excreted in the urine permanent per minute. Plasma concentration rather than whole blood consideration is used to calculate renal clearance.