The Fluid Mosaic Model of the cell membrane was proposed and described by S.J. Singer and G.L. Nicolson in 1972 and is now widely accepted.
The cell membrane is like a fluid at body temperature. Lipids, proteins, and glycoproteins are moving on the plasma membrane surface. When body temperature rises, the flexibility of the cell membrane decreases, causing disturbances of cell membrane functions, especially selective permeability is disturbed, causing severe consequences.
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