Plasma Protein-Rapid Revision

In this article, we will learn about plasma proteins, their sites of secretion, types, functions, and much more.

Keywords: Physiology|Plasma Protein| Albumin|Globulin| Fibrinogen

Table of contents

1. Introduction
2. Types:
   1. Main: 
   2. Others:
   3. A/G ratio is 1.7:1
3. Functions of plasma proteins:
   1.   Hormones
4. Plasma Proteins are synthesized by
5. Whipple’s classification of cell proteins:
6. Source  of plasma protein:
   1. Disclaimer:

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Introduction

Plasma is blood from which formed elements of blood (red blood corpuscles (RBC), White blood corpuscles WBC), and platelets (thrombocytes) are removed.

Proteins present in the plasma are known as plasma proteins.

Average amount: 6.4 gm -8.3 gm per decilitre of blood.

Types:

Main: 

Albumin 3-5 gm (4.8 gm )per decilitre of blood.

            Globulin  2-3 gm per decilitre of blood.

            Fibrinogen-0.3 gm per decilitre of blood.

Others:

Many other Plasma Proteins are present in tiny amounts.

A/G ratio is 1.7:1

Functions of plasma proteins:

1. Maintain colloidal osmotic pressure.

2. Coagulation of blood.

3. Maintain acid-base balance.

4. Transport functions

  Hormones

7. Tissue nutrition by forming trephines or carrel

8. Provide viscosity of blood.

Plasma Proteins are synthesized by

1. In embryo from the mesenchymal cells.
2. In adults

Albumin and fibrinogen from the liver.

Globulin from plasma cells, lymphocytes, tissue macrophages (reticuloendothelial system in liver, spleen, and bone marrow)

Whipple’s classification of cell proteins:

1. Labile Protein

2. Dispensable Protein

3. Indispensable protein or fixed cell protein.

Source  of plasma protein:

Food protein, and in starvation tissue protein.

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